Neuroprotective agents target molecular mechanisms of disease in ALS
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چکیده
منابع مشابه
Evaluation of neuroprotective effects of cobalamin (vitamin B12) in Parkinson's disease - Investigation of molecular mechanisms
Background & objectives: Parkinson's disease is one of the most common neurodegenerative diseases that its prevalence has increased in recent years. Although many efforts have been made to treat this disease, so far, no therapeutic approach has been found that can stop the destruction of dopaminergic cells in the substantia nigra. The aim of the present study was to investigate the effect of v...
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Parkinson's disease (PD) is one of the most common degenerative disorders of the central nervous system among the elderly. The disease is caused by the slow deterioration of the dopaminergic neurons in the substantia nigra. Treatment strategies to protect dopaminergic neurons from progressive damage have received much attention. However there is no effective treatment for PD. Traditional Chines...
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Mounting evidence suggests that lifestyle factors, especially nutrition are essential factor for healthy ageing. However, as a result of the increase in life expectance, neurodegenerative diseases like Alzheimer's and Parkinson's (AD and PD, respectively) are becoming an increasing burden, as aging is their main risk factor. Brain aging and neurodegenerative diseases of the elderly are characte...
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ژورنال
عنوان ژورنال: Drug Discovery Today
سال: 2015
ISSN: 1359-6446
DOI: 10.1016/j.drudis.2014.08.016